Muscarinic (M) Receptors in Coronary Circulation
نویسندگان
چکیده
منابع مشابه
P136: Role of Muscarinic Receptors in Schizophrenia
Schizophrenia is a severe psychiatric illness with a lifetime prevalence of ˜1% that imposes a huge toll on patients, their families and public health services worldwide. Delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior and negative symptoms constitute the core symptoms of schizophrenia. Although the neurotransmitter dopamine plays a prominent role in t...
متن کاملMuscarinic (M) receptors in coronary circulation: gene-targeted mice define the role of M2 and M3 receptors in response to acetylcholine.
OBJECTIVE Determining the role of specific muscarinic (M) receptor subtypes mediating responses to acetylcholine (ACh) has been limited by the specificity of pharmacological agents. Deletion of the gene for M5 receptors abolished response to ACh in cerebral blood vessels but did not affect dilation of coronary arteries. The goal of this study was to determine the M receptors mediating responses...
متن کاملEndothelin A-receptors and the coronary circulation
We review the role of endothelin (ET) A-receptors (R) on the coronary circulation. ET-1 maintains the normal coronary artery tone. ET-1 plasma levels are increased during and after coronary angioplasty and this increase is related to myocardial ischaemia rather than to mechanical artery injury. ETAR antagonists inhibit coronary artery vasoconstriction induced by ET release after coronary angiop...
متن کاملp136: role of muscarinic receptors in schizophrenia
schizophrenia is a severe psychiatric illness with a lifetime prevalence of ˜1% that imposes a huge toll on patients, their families and public health services worldwide. delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior and negative symptoms constitute the core symptoms of schizophrenia. although the neurotransmitter dopamine plays a prominent role in t...
متن کاملRoles of M 2 and M 4 muscarinic receptors in regulating acetylcholine release from myenteric
Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Science, Osaka Prefecture University, 1-1 Gakuen-cho, Sakai Osaka 599-8531, Japan, Department of Pharmacology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan and Division of neuronal Network, Department of Basic Medical Sciences, The Institute of Medical Science, The University of Toky...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2004
ISSN: 1079-5642,1524-4636
DOI: 10.1161/01.atv.0000130661.82773.ca